| ABSTRACT
Objective: To
evaluate the effect of aspheric intraocular
lenses on visual function in patients undergoing
cataract phacoemulsification surgery.
Patients and methods:
A prospective and observational study that
was conducted in ophthalmology department at
King Hussein Medical Center. Thirty consecutive
patients undergoing cataract phacoemulsification
with intraocular lens implantation by the same
surgeon, were examined for their visual function
and contrast sensitivity before and after surgery.
Both high and low contrast visual acuities were
evaluated and patient satisfaction regarding
surgery was graded as very satisfied, satisfied,
neutral, dissatisfied and very dissatisfied.
Patients with central nervous system, ocular
pathology or pre-operative complications affecting
visual function were excluded from the study.
Results: The
mean age of patients was 62.9 years with 16
males and 14 females. Eleven patients had contralateral
phacoemulsification with implantation of different
types of intraocular lens. One patient was found
to have a macular hole and was excluded from
the study. 93.3% of patients had log MAR best
corrected visual acuity of less than 0.1 under
high illumination. 56.7% of the patients were
very satisfied with the results of the aspheric
implant compared to 9.1% of the other implants,
which were used previously in the contralateral
eye. 6.7% and 36.4% of the two groups respectively
had light related problems.
Conclusion: Aspheric
intraocular lenses were associated with improvement
of mesopic contrast sensitivity, better image
quality and less glare. We advise to use them
routinely in patients undergoing cataract phacoemulsification
surgery except in cases of excessive preoperative
negative corneal aberrations.
Keywords:
Aspheric, traditional, contrast, satisfaction
and aberrations.
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Introduction
Biconvex spherical surfaces
create positive spherical aberration that is the peripheral
rays comes to a shorter focus than central rays resulting
in loss of contrast sensitivity1. Traditional
intraocular lenses are examples of those lenses that
induce positive spherical aberrations.
Normally the cornea has positive
spherical aberrations that offset the negative aberrations
attributed to the lens2. Small positive
spherical aberrations allow greater depth of field.
With aging, corneal aberrations increase and lenticular
aberrations turn into positive, resulting in more
positive spherical aberration and loss of contrast
sensitivity. Negative spherical aberration lenses
are recently used to offset the positive aberration
of the cornea. They should be precisely positioned;
otherwise high order aberrations such as coma will
result3.
Aspheric advanced optics intraocular
lenses have two aspheric surfaces to eliminate any
spherical aberrations produced by the lens. The optic
is asymmetrically biconvex with the anterior surface
steeper than the posterior. The lens power is uniform
throughout the optic surface, resulting in similar
diffraction of peripheral and paraxial rays. They
do not introduce new aberrations into the eye and
closely follow the optics of phakic eye keeping small
positive spherical aberrations with increased depth
of field and good contrast sensitivity4.
In this study we aimed
to evaluate the effectiveness of aspheric intraocular
lenses in patients undergoing cataract phacoemulsification
surgery. Some of our patients had a contralateral
phacoemulsification cataract surgery with a traditional
lens implant, which we compared with the recent surgery
done.
Patients and Methods
This prospective and observational
study was conducted at King Hussein Medical Center.
Thirty patients who underwent phacoemulsification
cataract surgery with implantation of an aspheric
intraocular lens by the same surgeon, were examined.
Inclusion criteria included patient's age between
50 and 85 years, intraocular lens power of 10-30 diopters
and potential visual acuity 0.6 log MAR or better
after surgery. Any patient with ocular pathology,
central nervous abnormality or pre-operative complications
affecting visual function was excluded from the study.
Both high and low contrast visual acuities were evaluated
using Log MAR visual acuity chart5. Patient
satisfaction regarding surgery was graded as very
satisfied where patients had no light related problem
or glare at all; satisfied as having minor light related
problem or glare; neutral, where no clear opinion
was given; dissatisfied as having significant problems
and very dissatisfied where they regretted having
the operation.
SRK formula was used
for intraocular lens calculation with target refraction
ranging between -1.02 to zero. Patients were given
the same standard pre-operative treatment of topical
phenylephrine 10% drops and tropicamide 1% drops.
Twenty eight patients had local anaesthesia (lidocaine
2% and bupivacaine 0.5%, 1:1 mixture) and 2 patients
had general anaesthesia. All patients had clear corneal
temporal incision of 3.00 mm. Capsulorrhexis was on
optic and 5.0 mm on average. Surgery time ranged from
8 minutes to 23 minutes (15.2 minutes on average).
Results
The age range was 50-78 years
(mean 62.9 years) with 1.14:1 male to female ratio.
Eleven patients had previous contralateral phacoemulsification
cataract surgery with implantation of another type
of intraocular lens.
Two third
of patients had zero log MAR best corrected visual
acuity and all patients had log MAR visual acuity
= 0.2 at high contrast level of illumination. At low
contrast illumination, seven patients (23.3%) had
zero log MAR best corrected visual acuity (figure
1). 56.7% of the patients were very satisfied
with the results of surgery and an additional 36.7%
were satisfied. Only two patients were neutral and
none of them were dissatisfied (figure
2). Among the eleven patients who had contralateral
traditional implant, seven patients were more satisfied
with aspheric variety and four patients found no difference.
Four patients (36.4%) of the traditional implant group
and two patients (6.7%) of the advanced optic group
had light related problems. Increase in eye sensibility
was found in 10% and unwanted images in 6.7% of the
eyes with the aspheric intraocular lens and posterior
capsular opacification occurred in one patient (table1).
Discussion
Despite the importance of
optical quality of an intraocular lens on visual outcomes
following cataract surgery, objective data on their
optical quality are not readily available, and manufacturing
standards are industry regulated 6. Traditional implants
are reported to cause light related discomfort in
33% of patients and driving problems in 40% 7.
In our series, 36.4% and 27.3% of the traditional
implant patients had such problems respectively.
Looking to figure one, we
can see that 28 patients had log MAR best corrected
visual acuity of less than 0.1 (corresponding to 6/9
Snellen's acuity) under high contrast illumination
and that 26 patients had the same level of visual
acuity under low illumination. The differences between
these figures are not statistically significant but
if we looked at the finest level of visual acuity
(zero log MAR or 6/6 Snellen's acuity) the figures
become significant (20 patients compared to 8, p<0.05).
We can conclude that aspheric intraocular lenses are
associated with the finest vision at high illumination
level.
Regarding patient satisfaction,
93.3% of the advanced optic implants and 63.6% of
the traditional implants were either very satisfied
or satisfied. These results were statistically significant
(p<0.05). If we look at the very satisfied group
of patients, we find the results more significant
(56.7% versus 9.1%, p<0.001).
Light related problems encountered
in traditional implant groups were comparable to reported
figures in literature7. In the advanced
optic aspheric implant patients, less light related
problems, driving problems, increased eye sensibility,
and unwanted images were seen. All of these results
except unwanted images were statistically significant
(Table 1).
We followed the patients for
6 months after the operation, particularly looking
for posterior capsular opacification; only one patient
of the aspheric implant (3.3%) had posterior capsular
opacification compared to two patients of the traditional
implant group (18.2%).
The comparison between different
types of implants in the same individual is associated
with less subjective error than comparing two different
groups of patients in terms of patient's satisfaction,
and side effects encountered after surgery. Among
the eleven patients who had contralateral traditional
implant, seven patients were more satisfied with the
aspheric implant and four patients found no difference.
Aspheric intraocular lenses
are suitable for those with previously LASIK treatment,
keratoconus, and other corneal aberrations8.
They are designed with no variation in power from
the center to the periphery providing predictable
outcomes for all patients including those with zonular
weakness or decentered pupils9. However,
they should not be used in excessive preoperative
corneal negative aberrations or post hyperopic LASIK
where the traditional implants with the counteracting
positive aberrations are advised.
The USA experience with aspheric
lenses was that they resulted in better image quality,
were more beneficial in young with larger pupils,
and were minimally affected by decentration. The Italians
found it to result in a dramatic decrease in posterior
capsular opacification, more forgiving in cases of
slight intraocular lens decentration and tilt and
associated with better depth of field and less glare
and dysphotopsia. The French experience was that they
were associated with improvement of mesopic contrast
sensitivity and had lower high order aberrations and
fewer glares3.
In conclusion, aspheric intraocular
lenses were associated with improvement of mesopic
contrast sensitivity, better image quality and less
glare. We advise to use them routinely in patients
undergoing cataract phacoemulsification surgery except
in cases of excessive preoperative negative corneal
aberrations.
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Figure
1: Best corrected visual acuity under high
and low contrast for aspheric intraocular lens.
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Figure
2 : Patients' satisfaction with their surgery
for the aspheric and traditional intraocular
lenses.
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Table
1 Side effects in relation to the type of intraocular
lens.
| Side
effect |
Number and percentage of patients with aspheric
IOL |
Number and percentage of patients with traditional
IOL |
p-value |
|
Light related problems |
2 (6.7%) |
4 (36.4%) |
P< 0.05 |
|
Unwanted images |
2 (6.7%) |
3 (27.3%) |
P< 0.02 |
|
Increased eye sensitivity |
3 (10%) |
4 (36.4%) |
P< 0.05 |
|
Driving problems |
0 |
3 (27.3%) |
P< 0.05 |
|
Posterior capsular opacification |
1 (3.3%) |
2 (18.2%) |
P< 0.02 |
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