Table of contents

Editorial

Meet the team
Abdulbari Bener, PhD, ITMA, MFPHM, FRSS
Original Contribution/Clinical Investigation
Rational Prescribing in Elderly

 

King Hussein Medical Center Experience With Aspheric Intraocular Lenses

Authors
Aymen Mdanat, FRCS, FRCOphth, Mousa Al-Madani, MD, Fahmi Aleikoor, FRCS(OPHTH)

Correspondence:
Aymen Mdanat, FRCS, FRCOphth
Senior consultant vitreoretinal surgeon,
the head of Ophthalmology Department at King Hussein Medical Center,
and chairman of Jordanian Ophthalmic Society.
address: P.O.Box 8141, Amman
11121 Jordan

ABSTRACT

Objective: To evaluate the effect of aspheric intraocular lenses on visual function in patients undergoing cataract phacoemulsification surgery.

Patients and methods: A prospective and observational study that was conducted in ophthalmology department at King Hussein Medical Center. Thirty consecutive patients undergoing cataract phacoemulsification with intraocular lens implantation by the same surgeon, were examined for their visual function and contrast sensitivity before and after surgery. Both high and low contrast visual acuities were evaluated and patient satisfaction regarding surgery was graded as very satisfied, satisfied, neutral, dissatisfied and very dissatisfied. Patients with central nervous system, ocular pathology or pre-operative complications affecting visual function were excluded from the study.

Results: The mean age of patients was 62.9 years with 16 males and 14 females. Eleven patients had contralateral phacoemulsification with implantation of different types of intraocular lens. One patient was found to have a macular hole and was excluded from the study. 93.3% of patients had log MAR best corrected visual acuity of less than 0.1 under high illumination. 56.7% of the patients were very satisfied with the results of the aspheric implant compared to 9.1% of the other implants, which were used previously in the contralateral eye. 6.7% and 36.4% of the two groups respectively had light related problems.

Conclusion: Aspheric intraocular lenses were associated with improvement of mesopic contrast sensitivity, better image quality and less glare. We advise to use them routinely in patients undergoing cataract phacoemulsification surgery except in cases of excessive preoperative negative corneal aberrations.

Keywords: Aspheric, traditional, contrast, satisfaction and aberrations.


Introduction

Biconvex spherical surfaces create positive spherical aberration that is the peripheral rays comes to a shorter focus than central rays resulting in loss of contrast sensitivity1. Traditional intraocular lenses are examples of those lenses that induce positive spherical aberrations.

Normally the cornea has positive spherical aberrations that offset the negative aberrations attributed to the lens2. Small positive spherical aberrations allow greater depth of field. With aging, corneal aberrations increase and lenticular aberrations turn into positive, resulting in more positive spherical aberration and loss of contrast sensitivity. Negative spherical aberration lenses are recently used to offset the positive aberration of the cornea. They should be precisely positioned; otherwise high order aberrations such as coma will result3.

Aspheric advanced optics intraocular lenses have two aspheric surfaces to eliminate any spherical aberrations produced by the lens. The optic is asymmetrically biconvex with the anterior surface steeper than the posterior. The lens power is uniform throughout the optic surface, resulting in similar diffraction of peripheral and paraxial rays. They do not introduce new aberrations into the eye and closely follow the optics of phakic eye keeping small positive spherical aberrations with increased depth of field and good contrast sensitivity4.

In this study we aimed to evaluate the effectiveness of aspheric intraocular lenses in patients undergoing cataract phacoemulsification surgery. Some of our patients had a contralateral phacoemulsification cataract surgery with a traditional lens implant, which we compared with the recent surgery done.


Patients and Methods

This prospective and observational study was conducted at King Hussein Medical Center. Thirty patients who underwent phacoemulsification cataract surgery with implantation of an aspheric intraocular lens by the same surgeon, were examined. Inclusion criteria included patient's age between 50 and 85 years, intraocular lens power of 10-30 diopters and potential visual acuity 0.6 log MAR or better after surgery. Any patient with ocular pathology, central nervous abnormality or pre-operative complications affecting visual function was excluded from the study. Both high and low contrast visual acuities were evaluated using Log MAR visual acuity chart5. Patient satisfaction regarding surgery was graded as very satisfied where patients had no light related problem or glare at all; satisfied as having minor light related problem or glare; neutral, where no clear opinion was given; dissatisfied as having significant problems and very dissatisfied where they regretted having the operation.

SRK formula was used for intraocular lens calculation with target refraction ranging between -1.02 to zero. Patients were given the same standard pre-operative treatment of topical phenylephrine 10% drops and tropicamide 1% drops. Twenty eight patients had local anaesthesia (lidocaine 2% and bupivacaine 0.5%, 1:1 mixture) and 2 patients had general anaesthesia. All patients had clear corneal temporal incision of 3.00 mm. Capsulorrhexis was on optic and 5.0 mm on average. Surgery time ranged from 8 minutes to 23 minutes (15.2 minutes on average).


Results

The age range was 50-78 years (mean 62.9 years) with 1.14:1 male to female ratio. Eleven patients had previous contralateral phacoemulsification cataract surgery with implantation of another type of intraocular lens.

Two third of patients had zero log MAR best corrected visual acuity and all patients had log MAR visual acuity = 0.2 at high contrast level of illumination. At low contrast illumination, seven patients (23.3%) had zero log MAR best corrected visual acuity (figure 1). 56.7% of the patients were very satisfied with the results of surgery and an additional 36.7% were satisfied. Only two patients were neutral and none of them were dissatisfied (figure 2). Among the eleven patients who had contralateral traditional implant, seven patients were more satisfied with aspheric variety and four patients found no difference. Four patients (36.4%) of the traditional implant group and two patients (6.7%) of the advanced optic group had light related problems. Increase in eye sensibility was found in 10% and unwanted images in 6.7% of the eyes with the aspheric intraocular lens and posterior capsular opacification occurred in one patient (table1).



Discussion

Despite the importance of optical quality of an intraocular lens on visual outcomes following cataract surgery, objective data on their optical quality are not readily available, and manufacturing standards are industry regulated 6. Traditional implants are reported to cause light related discomfort in 33% of patients and driving problems in 40% 7. In our series, 36.4% and 27.3% of the traditional implant patients had such problems respectively.

Looking to figure one, we can see that 28 patients had log MAR best corrected visual acuity of less than 0.1 (corresponding to 6/9 Snellen's acuity) under high contrast illumination and that 26 patients had the same level of visual acuity under low illumination. The differences between these figures are not statistically significant but if we looked at the finest level of visual acuity (zero log MAR or 6/6 Snellen's acuity) the figures become significant (20 patients compared to 8, p<0.05). We can conclude that aspheric intraocular lenses are associated with the finest vision at high illumination level.

Regarding patient satisfaction, 93.3% of the advanced optic implants and 63.6% of the traditional implants were either very satisfied or satisfied. These results were statistically significant (p<0.05). If we look at the very satisfied group of patients, we find the results more significant (56.7% versus 9.1%, p<0.001).

Light related problems encountered in traditional implant groups were comparable to reported figures in literature7. In the advanced optic aspheric implant patients, less light related problems, driving problems, increased eye sensibility, and unwanted images were seen. All of these results except unwanted images were statistically significant (Table 1).

We followed the patients for 6 months after the operation, particularly looking for posterior capsular opacification; only one patient of the aspheric implant (3.3%) had posterior capsular opacification compared to two patients of the traditional implant group (18.2%).

The comparison between different types of implants in the same individual is associated with less subjective error than comparing two different groups of patients in terms of patient's satisfaction, and side effects encountered after surgery. Among the eleven patients who had contralateral traditional implant, seven patients were more satisfied with the aspheric implant and four patients found no difference.

Aspheric intraocular lenses are suitable for those with previously LASIK treatment, keratoconus, and other corneal aberrations8. They are designed with no variation in power from the center to the periphery providing predictable outcomes for all patients including those with zonular weakness or decentered pupils9. However, they should not be used in excessive preoperative corneal negative aberrations or post hyperopic LASIK where the traditional implants with the counteracting positive aberrations are advised.

The USA experience with aspheric lenses was that they resulted in better image quality, were more beneficial in young with larger pupils, and were minimally affected by decentration. The Italians found it to result in a dramatic decrease in posterior capsular opacification, more forgiving in cases of slight intraocular lens decentration and tilt and associated with better depth of field and less glare and dysphotopsia. The French experience was that they were associated with improvement of mesopic contrast sensitivity and had lower high order aberrations and fewer glares3.

In conclusion, aspheric intraocular lenses were associated with improvement of mesopic contrast sensitivity, better image quality and less glare. We advise to use them routinely in patients undergoing cataract phacoemulsification surgery except in cases of excessive preoperative negative corneal aberrations.


Figure 1: Best corrected visual acuity under high and low contrast for aspheric intraocular lens.

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Figure 2 : Patients' satisfaction with their surgery for the aspheric and traditional intraocular lenses.

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Table 1 Side effects in relation to the type of intraocular lens.

Side effect Number and percentage of patients with aspheric IOL Number and percentage of patients with traditional IOL p-value
Light related problems 2 (6.7%) 4 (36.4%) P< 0.05
Unwanted images 2 (6.7%) 3 (27.3%) P< 0.02
Increased eye sensitivity 3 (10%) 4 (36.4%) P< 0.05
Driving problems 0 3 (27.3%) P< 0.05
Posterior capsular opacification 1 (3.3%) 2 (18.2%) P< 0.02

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References

1. Spherical aberrations from Wikipedia, the free encyclopedia. Available from http://en.wikipedia.org/wiki/Spherical_aberration.
2. Griffith EA. Wave front-customized intraocular lenses. Current Opinion in Ophthalmology 2004; 15: 358-364.
3. Available from http://www.escrs.org/Publications/Eurotimes/05September/pdf/B&Linsert.pdf
4. Tsubota K, Boxer BS, Wachler B, Azar DT. Hyperopia and presbyopia 2003, page 284.
5. Rosser DA, Laidlow DAH, Murdoch IE. The development of a "reduced logMAR" visual acuity chart for use in routine clinical practice. Br J Ophthalmol 2001; 85: 432-436
6. Mitchell L, Molteno ACB, Bevin DH, Sanderson G. Star testing: a novel evaluation of intraocular lens optical quality. Br J Ophthalmol 2006; 90: 586-592.
7. Tester R, Pace NL, Samore M, Olson RJ. Dysphotopsia in phakic and pseudophakic patients: incidence and relation to intraocular lens type(2). J Cataract Refract Surg 2000; 26: 810-816.
8. Chu YR, Talley-Rostov AR. Cataract Surgery: New Options, New Challenges. Review of ophthalmology July 2006.
9. IOL options in 2006. Available from
http://www.crstoday.com/PDF%20Articles/0106/CRST0106_f1_focus.pdf